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  • Elastin Products Company, Inc.
    P.O. Box 568
    Owensville, Missouri, USA 65066

  • Phone: 573-437-2193
    Fax: 573-437-4632
    email: epc@elastin.com

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$184.00

Isoamylphosphonyl-Glycyl-Prolyl-L-Alamine, dipotassium salt. F.W. 454

Prepared by the methodof Galardy and Grobelny(26).  Puritey is determined by thin layer chromatography and NMR.  The purity is 95%. A 1 µM concentration completely inhibits 20 µM concentration completely inhibits 20µM of collagenase from Clostridium histolyticum (K= 20 µM).  The inhibitor can be coupled to aminohexyl-agarose by reaction with EDC to yield an affinity gel (28) suitable for purification of collagenase (27).

Molecular Weight = 453.57

Exact Mass =453

Molecular Formula = C15H26K2N306P

Molecular Composition = 39.72% H 5.78% K 17.24% N 9.2% O 21.16% P 6.83%